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Omicron stays unhindered by most antibody treatments, show early tests

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3 years ago

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Omicron stays unhindered by most antibody treatments, show early tests

In the context of a global surge in Covid-19 cases, mainly caused by the highly spread Omicron variant, research has shown that antibody treatments that are effective against previous strains of coronavirus may not be effective against new variants.

According to a report in the journal Nature, some preprint publications indicate that Omicron is “fully or partially resistant to all currently available treatments based on these monoclonal antibodies.” Therefore, compared with other variants, many antibody therapy manufacturers have admitted that their products are much less effective on Omicron.

According to the report, the only two antibodies with strong evidence are sotrovimab developed by Vir Biotechnology in San Francisco, California, and GSK, headquartered in London. And DXP-604. US health officials said they will allocate sotrovimab to states based on the severity of Covid-19 and the number of infections and hospitalizations. However, many countries cannot obtain sotrovimab at all. Generally speaking, monoclonal antibody therapy for Covid-19, whether from a single antibody or a mixture of multiple antibodies, can prevent the virus from infecting human cells, thereby reducing the risk of viral infection by up to 85% through the following methods. In the case of Omicron, the researchers quoted in the report that even if the concentration is increased, the therapeutic concentration that should reduce virus replication by half cannot even reach the threshold.

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Olivier Schwartz, a virologist at the Pasteur Institute in Paris and co-author of one of the preprints, said: “We did not expect this change in the effectiveness of antibodies.”

Sotrovimab is the best antibody therapy available. However, the study found that the only two antibody therapies that maintain a certain degree of neutralization against Omicron are the therapies developed by AstraZeneca in Cambridge, England.

So far, compared to the highly infectious Delta strain, Omicron has been shown to be more infectious but less severe. Stuart Turville, a virologist at the Kirby Institute in Sydney, Australia, said that although the number of hospitalizations for the new variant has decreased so far, “if Omicron bites hard, it will be a disaster.” He is a co-author of the study. one. Preprint.

Omicron is the main variant of the United States. In the past two weeks, the number of new Covid-19 cases per day has more than tripled, reaching a record average of 480,000 cases. With dozens of infected workers being quarantined, American schools, hospitals and airlines are struggling.

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US vice president JD Vance, wife Usha and kids visit Jaipur’s iconic Amber Fort | Pics

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3 weeks ago

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April 24, 2025

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US vice president JD Vance, wife Usha and kids visit Jaipur’s iconic Amber Fort | Pics

US Vice President JD Vance, his wife Usha Vance, and their children visited the historical Amer Fort in Jaipur on April 22, 2025. The Vance family received a warm welcome at the Fort, where they were greeted with a traditional Rajasthani dance performance and elegantly decorated elephants. Second Lady Usha Vance, the wife of US vice president JD Vance, carries her daughter Mirabel as they watch a cultural performance at the Amber Fort in Jaipur.

Rajasthan CM Bhajanlal Sharma welcomed the Vance family as they visited the historic Amer Fort in Jaipur. The Vance family will depart for the US early Thursday morning. In related news, JD Vance and wife Usha attended Good Friday service at St. Peter’s Basilica in Vatican City. Vance also visited the Taj Mahal in Agra on April 23, 2025. Vance said that “good progress.

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In other news, Pope Francis’ funeral is set to start on Wednesday, and the J&K tourist hub has been completely shut today. On 4/20, celebrations across the US highlight cannabis culture and calls for legalization had been made towards a trade deal with India after meeting with “tough negotiator” Prime Minister Narendra Modi in New Delhi. The Vance family visited.

On April 22, 2025, US Vice President JD Vance, accompanied by his wife Usha Vance, and their three children, visited Jaipur’s historic Amber Fort. The family received a warm welcome, highlighted by traditional Rajasthani folk performances and a red carpet reception. As they entered the fort’s main courtyard, Jaleb Chowk, they were greeted by two elegantly decorated elephants named Chanda and Mala, raising their trunks in greeting. ​

During their visit, the Vances were joined by Rajasthan Chief Minister Bhajanlal Sharma and Deputy Chief Minister Diya Kumari, who guided them through the fort’s rich history and architectural marvels. The family also enjoyed cultural performances featuring traditional dances such as Kacchi Ghodi, Ghoomar, and Kalbeliya, offering a glimpse into the vibrant.

Usha Vance, dressed in a chic white shirt and patterned skirt, explored the fort alongside her family and dignitaries, embracing the cultural experience culture of Rajasthan This visit was part of Vice President Vance’s four-day official trip to India, aimed at strengthening bilateral relations between the United States and India. The Vance family departed for Washington.

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Bhajanlal Sharma welcomed the Vance family as they visited the historic Amer from Jaipur on April 24, concluding their cultural tour of India Upon their arrival at Amber Fort, the Vance family was greeted with traditional Rajasthani hospitality. Two elegantly decorated elephants, Chanda and Pushpa, adorned with silver ornaments, were stationed at the entrance welcome.

The family was also treated to a cultural performance featuring folk artists dressed in traditional Rajputi and Kalbelia attire, accompanied by musicians playing regional instruments. The vibrant rangolis and the overall festive atmosphere highlighted the rich cultural tapestry of Rajasthan The fort’s impressive courtyards and majestic structures.

Exploring the Fort’s Historical Significance

During their tour of Amber Fort, the Vance family explored various architectural marvels, including the Sheesh Mahal (Mirror Palace), known for its intricate mirror work and stunning design. They were accompanied by Rajasthan Chief Minister Bhajanlal Sharma and Deputy Chief Minister Diya Kumari, who provided insights into the fort’s history and significance.​

Engaging with Local Culture

Throughout their visit, Vice President Vance demonstrated a keen interest in engaging with The Vance family’s visit to Amber Fort was part local culture. He interacted with the folk artists and expressed appreciation for the traditional performances, reflecting a genuine curiosity and respect for India’s diverse cultural heritage.​

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