health and remedies
Protein partners have been found by researchers who may help to mend cardiac muscle.
The work is being carried out by researchers at the UNC School of Medicine, and could have a substantial impact on the development of future treatments for broken hearts. Researchers have found a way to reprogram scar tissue cells (fibroblasts) to become healthy heart muscle cells. The study was published in the journal Cell Stem Cell (cardiomyocytes) Researchers are looking into possibly treating or one day curing cardiac disease.
They used a gene activity-controlling protein called Ascl1, which is well recognised to be an essential protein for converting fibroblasts into neurons. Researchers hope to use this technique to give patients injections to transform harmful cells into helpful ones. Fibroblast over-activity underlies many major diseases and conditions including heart failure, chronic obstructive pulmonary disease, liver disease, kidney disease and the scar-like brain damage that occurs after a stroke. “Reprogramming fibroblasts has long been one of the important goals in the field of stem cell therapy,” Qian says. A team of researchers led by Professor Yingying Qian has developed a way to reprogram mice fibroblasts into cardiomyocytes, liver cells, and neurons. Qian’s team studied the variations in gene activity patterns and variables that control gene activity during these three separate reprogrammings. A team of researchers has discovered that converting fibroblasts into neurons activated genes related to cardiomyocytes. Ascl1, one of the master-programmer “transcription factor” proteins, was the cause of this activation. They were shocked to see that it significantly increased reprogramming efficiency by more than ten times.
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Holi 2024: We are eagerly awaiting the arrival of this festival of colors, which is quickly approaching. Every year, the nation celebrates Holi with great fanfare and extravagance. Holi commemorates the eternal love and marriage of Goddess Radha and Lord Krishna. In addition, Holi commemorates Lord Vishnu’s victory over Hiranyakashipu, highlighting the idea that good always triumphs over evil. Holi will be celebrated on March 25 this year. Holika Dahan, also known as Chhoti Holi, is observed the day before Holi. On the day of Holi, many customs and rites are observed throughout India. The cities of Barnsana and Nandgaon celebrate Lathmar Holi, whereas Vrindavan celebrates Phoolwali Holi.
Holi 2024: Here are some professional suggestions to avoid Bhang hangover, ranging from eating a balanced diet to sipping herbal tea.
During Holi, a variety of snacks and beverages are made to be enjoyed with loved ones. The colorful, crispy, and delectable Holi snacks range from gujia to rasmalai to namakpare. Thandai, a delightful concoction of milk, spices, and sweets, is the queen of the drink table. Bhang is among the primary draws of Holi. For its euphoric impact, thandai is sometimes blended with powdered paste made from the female cannabis plant’s leaves and flowers. But after the first euphoria wears off, there’s also the inevitable hangover the following morning.
Methods for overcoming a hangover
Hydrate the body: Hydration is crucial for managing a hangover caused by Bhang during Holi. Sip on lots of water to flush out toxins and replenish your body’s moisture.
Consume coconut water: Coconut water and other electrolyte-rich beverages can help replenish lost nutrients.
A balanced diet: blood sugar regulation and nausea reduction can be achieved by eating a well-balanced meal high in carbohydrates, proteins, and healthy fats.
Herbal teas and rest: Herbal teas with relaxing properties, such as peppermint or ginger, can ease stomach discomfort. Your body can mend itself by resting in a quiet, dark environment.
Limit alcohol intake: Limit your alcohol and cannabis intake to prevent symptoms from getting worse. As soon as symptoms develop or continue, get medical help.
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