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Protein partners have been found by researchers who may help to mend cardiac muscle.

Published

8 months ago

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Protein partners have been found by researchers who may help to mend cardiac muscle.

The work is being carried out by researchers at the UNC School of Medicine, and could have a substantial impact on the development of future treatments for broken hearts.  Researchers have found a way to reprogram scar tissue cells (fibroblasts) to become healthy heart muscle cells. The study was published in the journal Cell Stem Cell (cardiomyocytes) Researchers are looking into possibly treating or one day curing cardiac disease.

They used a gene activity-controlling protein called Ascl1, which is well recognised to be an essential protein for converting fibroblasts into neurons. Researchers hope to use this technique to give patients injections to transform harmful cells into helpful ones. Fibroblast over-activity underlies many major diseases and conditions including heart failure, chronic obstructive pulmonary disease, liver disease, kidney disease and the scar-like brain damage that occurs after a stroke. “Reprogramming fibroblasts has long been one of the important goals in the field of stem cell therapy,” Qian says. A team of researchers led by Professor Yingying Qian has developed a way to reprogram mice fibroblasts into cardiomyocytes, liver cells, and neurons. Qian’s team studied the variations in gene activity patterns and variables that control gene activity during these three separate reprogrammings. A team of researchers has discovered that converting fibroblasts into neurons activated genes related to cardiomyocytes. Ascl1, one of the master-programmer “transcription factor” proteins, was the cause of this activation. They were shocked to see that it significantly increased reprogramming efficiency by more than ten times.

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Food

Three unique vegan protein sources you should try if you follow a plant-based diet

Published

4 weeks ago

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May 9, 2023

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Three unique vegan protein sources you should try if you follow a plant-based diet

If you follow a plant-based diet, finding sources of protein can sometimes be a challenge. However, there are many vegan protein sources available that are both delicious and nutritious. Here are three unique vegan protein sources you should try:

  1. Tempeh

Tempeh is a traditional Indonesian food made from fermented soybeans. It has a slightly nutty flavor and a firm, chewy texture that makes it a great substitute for meat. Tempeh is also high in protein, with around 15 grams of protein per 100 grams. It is also a good source of iron, calcium, and probiotics, which can help support gut health.

Tempeh is versatile and can be used in a variety of dishes, including stir-fries, sandwiches, and salads. It can also be marinated or seasoned to add extra flavor.

  1. Seitan

Seitan, also known as wheat meat or wheat gluten, is made from wheat protein. It has a chewy, meaty texture and can be used as a substitute for meat in many dishes. Seitan is also high in protein, with around 25 grams of protein per 100 grams. It is also a good source of iron and other minerals.

Seitan can be used in a variety of dishes, including stir-fries, stews, and sandwiches. It can also be seasoned or flavored to add extra taste.

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  1. Nutritional Yeast

Nutritional yeast is a deactivated yeast that is high in protein and B-vitamins. It has a nutty, cheesy flavor and can be used as a seasoning or ingredient in a variety of dishes. Nutritional yeast is also a good source of fiber, which can help support digestion.

Nutritional yeast can be used as a seasoning for popcorn, roasted vegetables, and pasta dishes. It can also be used to make vegan cheese sauces and dressings.

In conclusion, if you follow a plant-based diet, there are many unique vegan protein sources available that are both delicious and nutritious. Tempeh, seitan, and nutritional yeast are just a few examples of the many vegan protein sources available. Incorporating these foods into your diet can help ensure that you are getting enough protein and other essential nutrients.

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