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Protein partners have been found by researchers who may help to mend cardiac muscle.

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Protein partners have been found by researchers who may help to mend cardiac muscle.

The work is being carried out by researchers at the UNC School of Medicine, and could have a substantial impact on the development of future treatments for broken hearts.  Researchers have found a way to reprogram scar tissue cells (fibroblasts) to become healthy heart muscle cells. The study was published in the journal Cell Stem Cell (cardiomyocytes) Researchers are looking into possibly treating or one day curing cardiac disease.

They used a gene activity-controlling protein called Ascl1, which is well recognised to be an essential protein for converting fibroblasts into neurons. Researchers hope to use this technique to give patients injections to transform harmful cells into helpful ones. Fibroblast over-activity underlies many major diseases and conditions including heart failure, chronic obstructive pulmonary disease, liver disease, kidney disease and the scar-like brain damage that occurs after a stroke. “Reprogramming fibroblasts has long been one of the important goals in the field of stem cell therapy,” Qian says. A team of researchers led by Professor Yingying Qian has developed a way to reprogram mice fibroblasts into cardiomyocytes, liver cells, and neurons. Qian’s team studied the variations in gene activity patterns and variables that control gene activity during these three separate reprogrammings. A team of researchers has discovered that converting fibroblasts into neurons activated genes related to cardiomyocytes. Ascl1, one of the master-programmer “transcription factor” proteins, was the cause of this activation. They were shocked to see that it significantly increased reprogramming efficiency by more than ten times.

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health and remedies

Winter-related ear popping: causes, remedies, and strategies for prevention

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Winter-related ear popping: causes, remedies, and strategies for prevention

If you live in a cold climate, you’re probably no stranger to the sensation of your ears popping when you step outside. This is caused by the change in pressure between the warm air inside your body and the cold air outside. While this is usually a harmless phenomenon, it can be quite annoying. In this article, we’ll explore the causes of winter-related ear popping, as well as some remedies and strategies for prevention.

One of the main causes of ear popping is a difference in air pressure. When you step outside into the cold air, the pressure outside is lower than the pressure inside your body. This difference in pressure can cause your ears to pop.

There are a few things you can do to ease the discomfort of ear popping. First, try yawning or swallowing. These activities can help equalize the pressure in your ears. You can also try chewing gum or sucking on candy. If you’re flying, drink plenty of fluids and avoid chewing gum during takeoff and landing.

There are also some preventive measures you can take to avoid ear popping. If you know you’ll be exposed to cold air, try to take a deep breath before you go outside. This will help equalize the pressure in your lungs and prevent your ears

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