Regeneron’s antibody cocktail may offer protection against Covid-19: Study
The experimental antibody cocktail which US President Donald Trump received when he tested positive for Covid-19 offers benefits against the novel coronavirus infection, according to a new study in animal models which provides more evidence of the clinical potential of the therapeutic.
While earlier studies had shown that the cocktail of two antibodies targeting the coronavirus spike protein could be used to neutralise the pathogen, scientists from the American biotechnology company Regeneron noted that further research in multiple animal models is needed to test the effectiveness of the formulation.
In the current study, published in the journal Science, the researchers tested REGN-COV2 in rhesus macaques, which manifest mild Covid-19 symptoms, and in golden hamsters, which show symptoms that are much more severe, including rapid weight loss. They found that when the cocktail was administered three days before challenging the macaques with the virus, the treatment almost completely blocked establishment of infection.
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