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Covid-19: Is an ‘Omicron-specific’ vaccine needed? Experts say it might come too late

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Covid-19: Is an ‘Omicron-specific’ vaccine needed? Experts say it might come too late

As the world frets over the need for an Omicron-specific vaccine against the coronavirus disease (Covid-19), several public health professionals and infectious disease experts interviewed by Nature have had mixed views on the matter. According to medics and researchers interviewed by the journal, it is unclear whether the scientific community will need to devote significant time and effort to developing a vaccine specifically against the highly circulating SARS-CoV-2 Omicron strain of the coronavirus, as the world’s Cases may flatten out before injections are approved in most places, or the next strain may be completely different from the current one, requiring again a different vaccine composition.

Debate: Why develop an Omicron-specific vaccine?

The earliest Covid-19 vaccines were based on the original SARS-CoV-2 strain first discovered in Wuhan, China. But since then, the coronavirus has undergone multiple mutations; the Omicron strain, which is capable of frequent transmission, contains more than 30 mutations in key regions of its genome, making it quite different from the original strain.

Given the changes in Omicron’s biology compared to the original virus, and the fact that the new strain is becoming the dominant variant in several countries around the world, the researchers came up with the idea of ​​updating the vaccine’s composition.

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Also, the protection provided by the booster is not permanent. While the UK health safety agency says a third dose of the vaccine reduces the risk of hospitalisation by 92% and the US Centers for Disease Control and Prevention (CDC) says it is 90% effective in preventing hospitalisations, everyone agrees that the protection is driven by boosters The firing also waned quickly. The UK study showed that the effectiveness against hospitalisation dropped from 92% to 83% just 10 weeks after the third dose was administered.

Notably, updated systems for existing vaccines such as influenza viruses already exist. The World Health Organization (WHO) has a team of experts that meets twice a year to recommend ingredients for the next season of vaccines, making it easier for health regulators in countries to follow up. There are also more than 100 laboratories and five WHO collaborating centres around the world conducting year-round surveillance, testing thousands of virus samples and predicting how the next influenza strain will develop.

However, there are some complications with the influenza vaccine model that replicates the coronavirus, especially given the Omicron variant.

Complete News Source : Hindustan Times

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Startups that use excerpts from their own pitch are sent legal notifications by Shark Tank India; the creator responds, “Kaise banega naya India?”

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Startups that use excerpts from their own pitch are sent legal notifications by Shark Tank India; the creator responds, “Kaise banega naya India?”

After getting a legal letter from Sony Pictures for copyright infringement, the subscription-based tea business Dorje Teas found itself in deep water for utilising footage from their own pitch on YouTube and Meta advertisements.

The founders of the subscription-based tea company Dorje Teas, Ishaan Kanoria and Sparsh Agarwal.

While many entrepreneurs, especially those with startups, have found transformation through the business reality TV series Shark Tank India, the narrative is slightly different for Dorje Teas, a subscription-based tea firm that ships organic and fresh-from-the-farm Darjeeling Tea to consumers throughout India. Sony Pictures Networks India slapped the firm with a legal notice, which has placed it in hot water.

Co-founder Sparsh Agarwal of the company, who brought Dorje Teas to Shark Tank India last year and raised funds of Rs 30 lakh for 15% equity from Anupam Mittal, Peyush Bansal, and Vineeta Singh, valued the business at Rs 2 crore, recently revealed on LinkedIn that they received a legal notice from Shark Tank India for utilising snippets of their own pitch.

Agarwal claims that they received a notification about copyright infringement for utilising these clips in YouTube and Meta advertisements. It appears that Sony Pictures has sent notice to other companies besides Dorje Teas. He said, “They’ve clamped down on every single startup that showed up on Shark Tank, so we’re not the only ones.”

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“I don’t understand why they would do this, even though I am aware of the copyright rules that justify it. After all, Dorje Teas and several other businesses, like Skippi, Assembly, Perfora, Hoovu Fresh, Beyond Snack, Wakao Foods, Nasher Miles, and many more, invest thousands of dollars each month to enhance Shark Tank content, which helps the Shark Tank India brand get free exposure and increase brand memory,” he continued.

Agarwal went on to call it a poor business choice that some executive or lawyer at Sony had made, adding that it “goes against the entire ethos of promoting small startups.”

Additionally, the focus of Shark Tank Season 3 has been on creating a new India and assisting the startup environment in India. “How will we construct a ‘new India’ in this manner?’” he questioned in a self-recorded video.

On social media, Agarwal was met with praise, while some contended that Sony’s actions were legitimate in theory. “Dear Sparsh, you must realise that ‘You are the content’ in this situation. You play a big part in content production. You posted the material that features you on your social media accounts (Facebook, Instagram, YouTube, and so on), but not on Sony’s. You might say that the traffic they were supposed to get was somehow redirected to them. A content strategist made the observation, “You are monetizing your social channels with the content they produce.”

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“The first person to provide a sneak peek in the content industry attracts greater attention. Furthermore, it’s possible that you agreed to sign a waiver giving them perpetual rights to the footage they shot. They said, “Verify your contract or try to recall signing any electronic documents on the filming locations that make this clear.

“You are investing lakhs of dollars to promote Shark Tank, while Shark Tank is investing billions of dollars to plan and publicise the programme that features your brand.” Simply alter your viewpoint, as another poster pointed out.

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