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Antibodies that might neutralize Omicron identified by scientists

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3 years ago

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Antibodies that might neutralize Omicron identified by scientists

In a recent study, an international team of scientists identified antibodies that can neutralize omicron and other SARS-CoV-2 variants.

These antibodies target areas of the viral spike protein, which remain essentially unchanged when the virus mutates. The results of the study were published in the journal Nature.

David Veesler said that by identifying the targets of these “broadly neutralizing” antibodies on the spike protein, it is possible to design vaccines and antibody treatments that are effective not only for the omicron variant but also for other variants that may appear in the future. Researcher at the Howard Hughes Medical Institute and associate professor of biochemistry at the University of Washington School of Medicine in Seattle.

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Also read: As Omicron advances Covid-19 cases, will 2022 be different?

“This discovery tells us that by focusing on antibodies against these highly conserved sites on the spike protein, there is a way to overcome the continuous evolution of the virus,” Wesseler said. Vir Biotechnology, in Switzerland. The lead authors of the study are Elisabetta Cameroni and Christian Saliba (Humabs), John E. Bowen (University of Washington Biochemistry) and Laura Rosen (Vir).

The omicron variant has 37 mutations in the spike protein, which is used to lock and invade cells. This is an unusually large number of mutations. It is believed that these changes partly explain why the variant can spread so quickly, thereby infecting people who have been vaccinated and reinfecting people who were previously infected.

“The main question we are trying to answer is: How does this series of mutations in the spike protein of the omicron variant affect its ability to bind to cells and evade immune system antibody responses,” Veesler said. Veesler and his colleagues speculate that a large number of omicron mutations may have accumulated during long-term infection in people with weakened immune systems, or accumulated during the spread of the virus from humans to animal species and then back. ]

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To assess the impact of these mutations, the researchers designed a disabling, non-replicating virus called a pseudovirus, which produces spike proteins on its surface, just like a coronavirus. They then created pseudoviruses with spike proteins with omicron mutations, as well as those found in the earliest variants found in the pandemic.

The researchers first observed how different versions of the spike protein bind to the protein on the cell surface, which the virus uses to attach and enter the cell. This protein is called the angiotensin converting enzyme 2 (ACE2) receptor.

Complete News Source : Hindustan Times

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Life Style

Malaika Arora’s silver sequined gown provides a spark of high-octane glamour as she begins her week.

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3 weeks ago

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December 31, 2024

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Malaika Arora’s silver sequined gown provides a spark of high-octane glamour as she begins her week.

Malaika Arora’s silver sequined gown provides a spark of high-octane glamour as she begins her week.

Malaika Arora, a renowned actress, model, and entrepreneur, is known for her stylish and glamorous fashion choices, with her recent stunning silver gown proving her reign as the queen of glam. Malaika wore a stunning Olivia Mark bodycon silver gown, adorned with sequins, creating a glittery and dazzling effect. The gown accentuated her frame and added an extra layer of glamour.

The gown’s unique styling, featuring full sleeves, a half-turtleneck design, and silver mesh detailing, adds sophistication and beauty to its shimmering body. Malaika paired her gown with silver heels, adding height and sparkle. She added an emerald ring and earrings for a pop of color and luxury, creating a stunning contrast that complemented the gown’s breathtaking design.

Malaika Arora wore a nude makeup palette, rosy lips, bold eyeliner, and sculpted cheekbones to create a feminine, polished look with a sleek updo and strands framing her face. Malaika’s recent appearance showcases her unmatched style and elegance, inspiring us that true fashion is not just about the outfit but also about confidence and grace.

Malaika Arora, the ever-glamorous Bollywood diva, continues to capture the spotlight with her impeccable sense of style. Known for her bold and chic fashion choices, Malaika recently stunned her fans as she stepped out in a show-stopping silver sequined gown that exuded high-octane glamour. The ensemble, which she wore to kick off her week, quickly became the talk of the town, and it’s easy to see why.

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The gown, with its striking metallic sheen and intricate sequin detailing, perfectly complemented Malaika’s fit physique and radiant personality. The silver hue added an element of sophistication, while the sparkling sequins caught the light, ensuring that all eyes were on her as she walked into the event. The dress was a blend of contemporary design with a hint of classic elegance, making it a perfect choice for a high-profile outing.

To complete her dazzling look, Malaika chose to pair the gown with minimalistic yet impactful accessories. A pair of sleek, silver stiletto heels elevated the gown’s appeal, adding height and elegance. She kept her accessories to a minimum, choosing delicate earrings and a simple bracelet.

letting the gown be the focal point of her ensemble. Her makeup was flawless, with bold eye makeup, a nude lip, and a glowing complexion that matched the glitz of her outfit. Her hair, styled in soft waves, complemented her chic and contemporary look, adding a touch of glamour that was both sophisticated and playful.

Malaika’s confidence is a major part of her allure, and it shines through every time she steps out in a show-stopping outfit like this one. Whether she’s walking the streets of Mumbai or attending a high-profile event, she has a unique way of commanding attention without being overbearing. This silver sequined gown further solidified her reputation as a fashion-forward icon in the industry.

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What makes Malaika’s style so magnetic is her ability to stay true to herself while constantly evolving. She knows how to push boundaries without ever compromising her own sense of identity. Her fashion choices, like this gown, highlight her love for all things glamorous, bold, and effortlessly chic.

As the week unfolded, Malaika’s look became the topic of conversation, inspiring fans and fashion enthusiasts alike to experiment with high-octane glamour in their own wardrobes. With this striking gown, Malaika Arora once again demonstrated why she remains one of the most influential fashion icons in the Bollywood industry, proving that she can turn heads and set trends with every appearance.

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