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Explained: When was IHU variant first discovered and its spread

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Explained: When was IHU variant first discovered and its spread

In the spread of Omicron coronavirus variants, the discovery of a new strain that emerged in France has attracted the attention of experts from all over the world. It was named “IHU”, which caused concerns about a new wave of infections.

This variant has 46 mutations and 37 deletions in its genetic code, which is more than Omicron. Many of these affect the spike protein.

This variant is a sub-family of B.1.640, and its discovery was announced by researchers at Méditerranée Infection in Marseille, which is part of the French Hospital University (IHU, or University Hospital Research Institute)-hence the name. It has been classified as B.1.640.2. When was IHU first discovered?

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According to Forbes, the first known case of a variant of IHU was discovered in mid-November 2021. This predates Omicron’s official discovery (November 24).

The new variant was discovered in a French man returning from Cameroon, Africa (Omicron was also found on the continent). He began to develop respiratory symptoms and was tested for Covid-19. The sample returned positive and there is a B.1.640.2 variant.

Read also | 5 great things about IHU variants

Since then, 11 more cases have been reported in the same geographic area in southwestern France.

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More information on the B.1.640 pedigree

The pedigree is not new. According to data from Exposure.info, an open source database of Covid-19 resources and epidemiological data, B.1.640 was first detected on January 1, 2021. It said that so far, 400 infections related to this lineage have been identified.

The outbreak information further reported that B.1.640 cases were detected in as many as 19 countries/regions, including one from India. The Indian case was detected from 89,763 sequences reported in the global database.

France (287) reported the most cases of the B.1.640 variant, followed by Congo (39), Germany (17) and the United Kingdom (16).

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Do IHU variants spread faster?

So far, only a dozen cases have been reported in France. No other countries have found any new cases of new variants. It is not clear whether B.1.640.2 is stronger or spread faster than other previously known coronavirus strains.

This is why the World Health Organization (WHO) has not yet considered this variant of IHU as a variant of interest, a variant of interest, or even a variant under investigation.

Based on a preprinted paper published on MedRxiv, it is too early to speculate on the virological, epidemiological or clinical characteristics of this variant of IHU.

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Complete News Source : Hindustan Times

Tollywood

Day 6 box office receipts for Game Changer: Ram Charan’s film takes another hit, earning over ₹110 crore

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Day 6 box office receipts for Game Changer: Ram Charan’s film takes another hit, earning over ₹110 crore

Game Changer box office collection day 6: Ram Charan and Kiara Advani-starrer released in theatres on January 10.
Game Changer box office collection: Ram Charan, Kiara Advani-Game Changer is one the first big releases of this year, and came with huge audience expectations. However the film opened to mixed reviews and has performed decently at the box office. As per the latest version of Sacnilk.com, Game Changer has minted ₹6.11 crore in its sixth day of release. Game Changer is directed by Shankar.

Game Changer box office collection

The report states that Game Changer has now crossed the ₹110 crore mark at the box office. It minted ₹5.55 crore on its first Wednesday, which is the lowest for the film so far. The film had seen a slight growth on its fifth day of release, with ₹10 crore net. The overall collections now stand at ₹112.26 crore.

Game Changer minted ₹51 crore on its opening day, and saw a dip in collections on its second day with ₹21.6 crore. Day three collections were at ₹15.9 crore whereas day four net was ₹7.65 crore. The film saw a sharp decline in its weekdays and is yet to recover. Game Changer is facing stiff competition from a number of releases, which includes Nandamuri Balakrisha’s Daaku Maharaj, Unni Mukundan’s Marco and Allu Arjun’s Pushpa 2: The Rule.

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More details

Amid box office concerns for the film, a pirated version of Game Changer was allegedly aired on a local TV channel and shown in buses. Screenshots of the same surfaced on X, which caught the attention of producer Sreenivas Kumar. He took to his X account to demand strict action on it.

A few days ago, the makers of the film had filed a complaint against individuals for allegedly leaking a pirated version of the film online. The complaint also states that before the film’s release, the producers and a few team members were threatened through social media and messaging platforms like WhatsApp, wherein the same alleged pirates demanded money from producers and threatened to leak the pirated version if their demands were not fulfilled.

Game Changer is directed by Shankar and stars Ram Charan, Kiara Advani, and SJ Suryah. The film has also been released in Tamil, Kannada, and Malayalam.

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