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2022 Newborn Screening (NBS) Awareness Month: India Currently Offers Test

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2022 Newborn Screening (NBS) Awareness Month: India Currently Offers Test

It might be difficult for paediatricians to make an early diagnosis of inborn metabolic errors (IEM) because the majority of these illnesses have no symptoms when a baby is first born. The majority of IEM instances are discovered a few days or even a few years after birth, by which point the brain has already suffered irreparable damage that puts the patient’s life in danger or has caused additional disabilities.

The most crucial test to identify these conditions early is newborn screening (NBS), which allows for early intervention and therapy for the kid. This article will tell you everything you need to know about the newborn screening tests that are now available in India, the state of newborn screening testing there, and any potential future trends. September is Newborn Screening Awareness Month.

India’s current newborn screening test options

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Dr. Suresh Birajdar, a neonatologist and paediatrician at Motherhood Hospital in Kharghar, stated in an interview with HT Lifestyle that “the screening is done before babies are discharged from the hospital, or shortly after birth. The disorders that are examined during newborn screening have a history of seriously affecting children’s or infants’ health. Physical and intellectual problems can be avoided by identifying these disorders quickly and treating them. When it comes to metabolic and genetic abnormalities, newborn screening (NBS) is crucial since early diagnosis and treatment can help to avert both physical and mental impairments as well as life-threatening illnesses.

In response to a question about the procedure in our nation, he stated, “In India, newborn screening is done to determine whether the child has any issues, such as hearing loss, congenital hypothyroidism, congenital adrenal hyperplasia (CAH), glucose-6-phosphate dehydrogenase (G6PD) deficiency, and a few other metabolic conditions. If not treated before the age of six months, congenital hearing loss is a serious disorder that can affect speech and hearing permanently. Another frequent condition in infants and one of the preventable causes of intellectual impairment is congenital hypothyroidism.

Congenital adrenal hyperplasia can result in mortality, morbidity, or genital abnormalities if it is not diagnosed at birth, the doctor warned. In our nation, G6PD deficiency is a frequent illness that can lead to anaemia and jaundice in youngsters. The newborns should also be screened for diseases like phenylketonuria, homocystinuria, alkaptonuria, galactosemia, sickle cell anaemia, hemoglobinopathies, heart issues, mucopolysaccharidosis type 1, severe combined immunodeficiency (SCID), cystic fibrosis, biotinidase deficiency, maple syrup urine disease, medium-chain acyl-CoA dehydrogen

Dr. Suresh Birajdar elaborated, “After allowing the paper to dry, it is sent to the laboratory, where numerous different newborn screening tests are performed, explaining that newborn screening is a blood test that requires a few drops of blood to be collected on a special filter paper by pricking the heel of the child. Tandem mass spectrometry is the name of the technique utilised to conduct these tests. The baby is unharmed as a result of the heel poke. Each baby receives a lancet, a specialist needle, and there is no chance of infection. Through screening, more than 100 metabolic and genetic disorders can be found.

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India’s newborn screening programme is currently inactive.

Dr. Suresh Birajdar noted that congenital cardiac disorders and genetic anomalies are more common in infants and added, “Due to parents’ increased awareness about NBS, they are not skipping the tests as they are proactive when it comes to the child’s health. Now that hospitals and doctors are advising couples about screening to find various health risks in the babies, NBS has become a priority. Along with India, NBS is successful in many other nations, thus parents should be urged to choose the screening option for their newborns. The NBS is in demand because infants are having more metabolic, endocrine, genetic, and haemoglobin issues.

Indian new-born screening test trends to watch

If not identified and treated in a timely manner, inborn metabolic errors, or IEM, can be harmful and even fatal. IEM cause physical issues and damage to the brain. Even if a kid has a disease, there is a chance that they won’t exhibit any symptoms of it when they are delivered, according to Dr. Suresh Birajdar. In contrast, NBS can identify and identify these problems at birth and assist the child in leading a healthy life. Amino acid disorders, fatty acid disorders, organic acid disorders, endocrine diseases, and haemoglobin problems are all testable by NBS.

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Thug Life Movie Review & Release Live Updates: Kamal Haasan’s Bold New Venture – Is it the Hit We Expected?

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Thug Life Movie Review & Release Live Updates: Kamal Haasan’s Bold New Venture – Is it the Hit We Expected?

Kamal Haasan’s Bold New Venture

Kamal Haasan, the versatile legend of Indian cinema, is back on the big screen with his latest thriller, Thug Life. After weeks of anticipation and a gripping promotional campaign, fans have eagerly awaited the release of this high-octane action drama. The movie, directed by debutant director Arvind Rao, promises to showcase Haasan in a never-before-seen avatar, leading to sky-high expectations. So, does Thug Life live up to the hype? In this blog, we bring you an in-depth review of the film, along with live updates from the first-day box office response. Is Thug Life the next blockbuster hit Kamal Haasan fans have been waiting for?

A Thrilling First Look: What’s Thug Life All About?
At its core, Thug Life is an action-packed thriller that explores the lives of notorious criminals, their complex relationships with law enforcement, and the grey areas of morality. Kamal Haasan plays Vikram Singh, a larger-than-life anti-hero with a troubled past who finds himself caught between the law and the underworld. The film also stars an ensemble cast, including the brilliant actress Simran, who plays a key role as Vikram’s moral compass.

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From the first teaser, it’s clear that Thug Life is set against the backdrop of a gritty urban world, filled with explosive action sequences, intense drama, and gripping twists. The film promises to delve deep into themes of justice, vengeance, and personal redemption. Kamal’s performance, combined with the intriguing premise, has set the stage for a grand theatrical release.

Plot and Direction: The Power of Storytelling
Thug Life is crafted in a fast-paced manner, with suspense building at every corner. The screenplay is written in a way that constantly keeps the audience on edge, making them question the true intentions of the characters. The film’s direction by Arvind Rao has been appreciated for its bold approach in showcasing complex characters and real-world dilemmas.

Kamal Haasan, known for his ability to transform into any character, does not disappoint here. He brings his unparalleled experience to the table, portraying a character who walks the thin line between good and evil. His performance is undoubtedly one of the highlights of the film.

Simran’s portrayal of Maya, a fierce and intelligent woman who challenges Vikram’s decisions, complements Haasan’s character beautifully. Their chemistry on screen elevates the emotional stakes, making the action sequences more impactful.

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Is the Action Worth the Hype?
The action sequences in Thug Life are nothing short of spectacular. From high-speed chases to hand-to-hand combat, the film delivers thrills on every front. The choreography, especially in the fight scenes, stands out for its fluidity and precision. Kamal Haasan, known for his commitment to physical transformation, performs many of the stunts himself, showcasing his dedication to the craft.

One of the standout moments is a tense sequence set in an abandoned warehouse where Vikram faces off against a group of armed criminals. The scene is intense, and the cinematography captures the chaos and confusion, making it a thrilling experience.

Music & Sound Design: A Powerful Impact
The film’s music, composed by the talented Anirudh Ravichander, perfectly complements the high-octane action and dramatic moments. Tracks like “Thug Life Anthem” and “Vikram’s Vengeance” have already started to trend on music platforms, and it’s easy to see why. The music amplifies the tension and excitement, enhancing the overall cinematic experience.

The sound design deserves special mention. Whether it’s the ominous hum during a quiet moment or the deafening roar during action sequences, the sound elevates the tension and immerses the audience in the world of Thug Life.

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Live Box Office Updates: A Promising Start
As the clock strikes midnight, audiences flock to theaters for the first showings of Thug Life. Early reviews on social media are buzzing with excitement, praising Kamal Haasan’s return to form and the gripping narrative. The film’s powerful action sequences and engaging storyline seem to have hit the right chord with fans.

Box office analysts predict a solid opening for Thug Life. With strong pre-release bookings, particularly in Chennai, Mumbai, and Bengaluru, the film is set for a roaring start. Kamal Haasan’s massive fan base is ensuring long lines at theaters, with advance bookings already sold out in several locations.

Reports from the first-day collections are already rolling in, and the numbers look promising. It’s expected that Thug Life will gross over ₹15 crore on its opening day, making it one of the highest openings for Kamal Haasan in recent years.

The Verdict: Is Thug Life Impressive?
Without a doubt, Thug Life is a powerful cinematic experience that showcases Kamal Haasan in peak form. The film succeeds in offering a gripping storyline, memorable characters, and a stellar performance from its lead. The action sequences and emotional depth set it apart from typical masala entertainers, and its themes resonate with today’s audience.

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While the plot may feel familiar to those who have watched similar thrillers, Thug Life distinguishes itself with its sharp direction, compelling performances, and high-quality production values. If you’re a fan of action films with emotional depth, this is a movie you won’t want to miss.

Rating: 4/5 – A must-watch for Kamal Haasan fans and action movie lovers alike.

Live Updates: Is Thug Life Making Waves?
10:00 AM – First Show Starts:
The first show has begun! Fans are already praising Kamal Haasan’s power-packed performance. Social media is flooded with reactions as people seem impressed with the intense action sequences.

12:30 PM – Early Box Office Numbers:
Thug Life is seeing a great response at the box office. Early reports show packed theaters in Chennai, Hyderabad, and Bengaluru. Looks like Kamal Haasan is in for a hit!

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3:00 PM – Social Media Buzz:
The film’s action and Kamal Haasan’s performance are trending on Twitter and Instagram. Fans are calling it his best role in years. Many are also impressed with the music by Anirudh.

6:00 PM – Fan Reactions:
The film continues to dominate social media as fans share videos from theaters. There’s a lot of love for the film’s emotional depth, making it clear that Thug Life is a crowd favorite.

Final Thoughts:
With such a fantastic opening, Thug Life looks set to make waves at the box office. Kamal Haasan’s stellar performance and the film’s impressive direction ensure that this thriller is more than just a typical action flick – it’s a cinematic experience.

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