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PTSD risk is linked to certain brain responses to stressful stress

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PTSD risk is linked to certain brain responses to stressful stress

According to the largest prospective study of its kind, people who were exposed to potentially dangerous scenarios and who had lower hippocampal activity had more severe posttraumatic stress disorder (PTSD) symptoms in the days and weeks that followed the event.

This relationship between decreased hippocampal activity and the chance of developing PTSD was especially apparent in people who had more defensive reflexive reflexes to being startled.

According to this study, which was published in the journal Neurosci, those who react more defensively to potentially dangerous occurrences may find it more difficult to determine whether an event is risky or not. They are also more likely to experience severe forms of PTSD, which include symptoms like being constantly alert for danger, engaging in self-destructive behaviour like binge drinking or speeding, having trouble falling asleep and staying awake, being irritable, having angry outbursts, and having nightmares.

According to senior author Vishnu Murty, PhD, assistant professor of psychology and neuroscience at Temple University, “these findings are important both to identify specific brain responses associated with vulnerability to develop PTSD, and to identify potential treatments focused on memory processes for these individuals to prevent or treat PTSD.”

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The national Advancing Understanding of Recovery after Trauma (AURORA) Study, a collaboration between multiple institutions, is financed by the National Institutes of Health, charitable foundations like One Mind, and partnerships with top technology firms. Samuel McLean, MD, MPH, head of the UNC Institute for Trauma Recovery and professor of psychiatry and emergency medicine at the University of North Carolina School of Medicine, serves as the organising primary investigator.

Researchers can use data from patient participants who visit emergency rooms at hospitals around the nation after suffering trauma from vehicle accidents or other traumatic situations thanks to AURORA. AURORA’s main objective is to promote the creation and evaluation of preventive and therapeutic interventions for people who have endured traumatic situations.

Only a small percentage of trauma survivors get PTSD, which is linked to greater sensitivity to danger and a reduced capacity to activate neuronal pathways that retrieve emotional memories, according to AURORA scientists. However, it is unclear how these two processes interact to raise the chance of getting PTSD. Murty and colleagues studied the brain and behavioural reactions of people two weeks after trauma to better understand these processes.

Researchers discovered that the individuals with the most defensive reactions to startling events following trauma had the least activity in their hippocampus and the least activity in their hippocampus, along with laboratory and survey-based assessments for trauma.

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According to Busra Tanriverdi, the study’s principal researcher and a doctoral student at Temple University, “among these people, increased defensive reactions to dangers may bias them against learning information about what is happening so that they can determine what is safe and what is harmful.” These findings point to a crucial PTSD biomarker that is concerned with how survivors of trauma create and recall memories.

According to McLean, an author on the publication, “these most recent findings add to our list of AURORA discoveries that are aiding us in understanding the differences between people who go on to acquire posttraumatic stress disorder and those who do not.” Studies that concentrate on the immediate aftermath of trauma are crucial because they help us better understand how PTSD manifests itself and how to prevent and cure it.

According to Brandon Staglin, president of One Mind, “Since beginning our financial support of the AURORA Study in 2016, we remain steadfast in our commitment to helping AURORA investigators make significant discoveries and to bridge the gaps that exist in mental health research funding and patient support.”

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Holi 2024: Inside, professional advice on overcoming a Bhang hangover

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Holi 2024: Inside, professional advice on overcoming a Bhang hangover

Holi 2024: We are eagerly awaiting the arrival of this festival of colors, which is quickly approaching. Every year, the nation celebrates Holi with great fanfare and extravagance. Holi commemorates the eternal love and marriage of Goddess Radha and Lord Krishna. In addition, Holi commemorates Lord Vishnu’s victory over Hiranyakashipu, highlighting the idea that good always triumphs over evil. Holi will be celebrated on March 25 this year. Holika Dahan, also known as Chhoti Holi, is observed the day before Holi. On the day of Holi, many customs and rites are observed throughout India. The cities of Barnsana and Nandgaon celebrate Lathmar Holi, whereas Vrindavan celebrates Phoolwali Holi.

Holi 2024: Here are some professional suggestions to avoid Bhang hangover, ranging from eating a balanced diet to sipping herbal tea.

During Holi, a variety of snacks and beverages are made to be enjoyed with loved ones. The colorful, crispy, and delectable Holi snacks range from gujia to rasmalai to namakpare. Thandai, a delightful concoction of milk, spices, and sweets, is the queen of the drink table. Bhang is among the primary draws of Holi. For its euphoric impact, thandai is sometimes blended with powdered paste made from the female cannabis plant’s leaves and flowers. But after the first euphoria wears off, there’s also the inevitable hangover the following morning.

Methods for overcoming a hangover

Hydrate the body: Hydration is crucial for managing a hangover caused by Bhang during Holi. Sip on lots of water to flush out toxins and replenish your body’s moisture.

Consume coconut water: Coconut water and other electrolyte-rich beverages can help replenish lost nutrients.

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A balanced diet: blood sugar regulation and nausea reduction can be achieved by eating a well-balanced meal high in carbohydrates, proteins, and healthy fats.

Herbal teas and rest: Herbal teas with relaxing properties, such as peppermint or ginger, can ease stomach discomfort. Your body can mend itself by resting in a quiet, dark environment.

Limit alcohol intake: Limit your alcohol and cannabis intake to prevent symptoms from getting worse. As soon as symptoms develop or continue, get medical help.

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