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PTSD risk is linked to certain brain responses to stressful stress

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PTSD risk is linked to certain brain responses to stressful stress

According to the largest prospective study of its kind, people who were exposed to potentially dangerous scenarios and who had lower hippocampal activity had more severe posttraumatic stress disorder (PTSD) symptoms in the days and weeks that followed the event.

This relationship between decreased hippocampal activity and the chance of developing PTSD was especially apparent in people who had more defensive reflexive reflexes to being startled.

According to this study, which was published in the journal Neurosci, those who react more defensively to potentially dangerous occurrences may find it more difficult to determine whether an event is risky or not. They are also more likely to experience severe forms of PTSD, which include symptoms like being constantly alert for danger, engaging in self-destructive behaviour like binge drinking or speeding, having trouble falling asleep and staying awake, being irritable, having angry outbursts, and having nightmares.

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According to senior author Vishnu Murty, PhD, assistant professor of psychology and neuroscience at Temple University, “these findings are important both to identify specific brain responses associated with vulnerability to develop PTSD, and to identify potential treatments focused on memory processes for these individuals to prevent or treat PTSD.”

The national Advancing Understanding of Recovery after Trauma (AURORA) Study, a collaboration between multiple institutions, is financed by the National Institutes of Health, charitable foundations like One Mind, and partnerships with top technology firms. Samuel McLean, MD, MPH, head of the UNC Institute for Trauma Recovery and professor of psychiatry and emergency medicine at the University of North Carolina School of Medicine, serves as the organising primary investigator.

Researchers can use data from patient participants who visit emergency rooms at hospitals around the nation after suffering trauma from vehicle accidents or other traumatic situations thanks to AURORA. AURORA’s main objective is to promote the creation and evaluation of preventive and therapeutic interventions for people who have endured traumatic situations.

Only a small percentage of trauma survivors get PTSD, which is linked to greater sensitivity to danger and a reduced capacity to activate neuronal pathways that retrieve emotional memories, according to AURORA scientists. However, it is unclear how these two processes interact to raise the chance of getting PTSD. Murty and colleagues studied the brain and behavioural reactions of people two weeks after trauma to better understand these processes.

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Researchers discovered that the individuals with the most defensive reactions to startling events following trauma had the least activity in their hippocampus and the least activity in their hippocampus, along with laboratory and survey-based assessments for trauma.

According to Busra Tanriverdi, the study’s principal researcher and a doctoral student at Temple University, “among these people, increased defensive reactions to dangers may bias them against learning information about what is happening so that they can determine what is safe and what is harmful.” These findings point to a crucial PTSD biomarker that is concerned with how survivors of trauma create and recall memories.

According to McLean, an author on the publication, “these most recent findings add to our list of AURORA discoveries that are aiding us in understanding the differences between people who go on to acquire posttraumatic stress disorder and those who do not.” Studies that concentrate on the immediate aftermath of trauma are crucial because they help us better understand how PTSD manifests itself and how to prevent and cure it.

According to Brandon Staglin, president of One Mind, “Since beginning our financial support of the AURORA Study in 2016, we remain steadfast in our commitment to helping AURORA investigators make significant discoveries and to bridge the gaps that exist in mental health research funding and patient support.”

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Thug Life Movie Review & Release Live Updates: Kamal Haasan’s Bold New Venture – Is it the Hit We Expected?

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Thug Life Movie Review & Release Live Updates: Kamal Haasan’s Bold New Venture – Is it the Hit We Expected?

Kamal Haasan’s Bold New Venture

Kamal Haasan, the versatile legend of Indian cinema, is back on the big screen with his latest thriller, Thug Life. After weeks of anticipation and a gripping promotional campaign, fans have eagerly awaited the release of this high-octane action drama. The movie, directed by debutant director Arvind Rao, promises to showcase Haasan in a never-before-seen avatar, leading to sky-high expectations. So, does Thug Life live up to the hype? In this blog, we bring you an in-depth review of the film, along with live updates from the first-day box office response. Is Thug Life the next blockbuster hit Kamal Haasan fans have been waiting for?

A Thrilling First Look: What’s Thug Life All About?
At its core, Thug Life is an action-packed thriller that explores the lives of notorious criminals, their complex relationships with law enforcement, and the grey areas of morality. Kamal Haasan plays Vikram Singh, a larger-than-life anti-hero with a troubled past who finds himself caught between the law and the underworld. The film also stars an ensemble cast, including the brilliant actress Simran, who plays a key role as Vikram’s moral compass.

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From the first teaser, it’s clear that Thug Life is set against the backdrop of a gritty urban world, filled with explosive action sequences, intense drama, and gripping twists. The film promises to delve deep into themes of justice, vengeance, and personal redemption. Kamal’s performance, combined with the intriguing premise, has set the stage for a grand theatrical release.

Plot and Direction: The Power of Storytelling
Thug Life is crafted in a fast-paced manner, with suspense building at every corner. The screenplay is written in a way that constantly keeps the audience on edge, making them question the true intentions of the characters. The film’s direction by Arvind Rao has been appreciated for its bold approach in showcasing complex characters and real-world dilemmas.

Kamal Haasan, known for his ability to transform into any character, does not disappoint here. He brings his unparalleled experience to the table, portraying a character who walks the thin line between good and evil. His performance is undoubtedly one of the highlights of the film.

Simran’s portrayal of Maya, a fierce and intelligent woman who challenges Vikram’s decisions, complements Haasan’s character beautifully. Their chemistry on screen elevates the emotional stakes, making the action sequences more impactful.

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Is the Action Worth the Hype?
The action sequences in Thug Life are nothing short of spectacular. From high-speed chases to hand-to-hand combat, the film delivers thrills on every front. The choreography, especially in the fight scenes, stands out for its fluidity and precision. Kamal Haasan, known for his commitment to physical transformation, performs many of the stunts himself, showcasing his dedication to the craft.

One of the standout moments is a tense sequence set in an abandoned warehouse where Vikram faces off against a group of armed criminals. The scene is intense, and the cinematography captures the chaos and confusion, making it a thrilling experience.

Music & Sound Design: A Powerful Impact
The film’s music, composed by the talented Anirudh Ravichander, perfectly complements the high-octane action and dramatic moments. Tracks like “Thug Life Anthem” and “Vikram’s Vengeance” have already started to trend on music platforms, and it’s easy to see why. The music amplifies the tension and excitement, enhancing the overall cinematic experience.

The sound design deserves special mention. Whether it’s the ominous hum during a quiet moment or the deafening roar during action sequences, the sound elevates the tension and immerses the audience in the world of Thug Life.

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Live Box Office Updates: A Promising Start
As the clock strikes midnight, audiences flock to theaters for the first showings of Thug Life. Early reviews on social media are buzzing with excitement, praising Kamal Haasan’s return to form and the gripping narrative. The film’s powerful action sequences and engaging storyline seem to have hit the right chord with fans.

Box office analysts predict a solid opening for Thug Life. With strong pre-release bookings, particularly in Chennai, Mumbai, and Bengaluru, the film is set for a roaring start. Kamal Haasan’s massive fan base is ensuring long lines at theaters, with advance bookings already sold out in several locations.

Reports from the first-day collections are already rolling in, and the numbers look promising. It’s expected that Thug Life will gross over ₹15 crore on its opening day, making it one of the highest openings for Kamal Haasan in recent years.

The Verdict: Is Thug Life Impressive?
Without a doubt, Thug Life is a powerful cinematic experience that showcases Kamal Haasan in peak form. The film succeeds in offering a gripping storyline, memorable characters, and a stellar performance from its lead. The action sequences and emotional depth set it apart from typical masala entertainers, and its themes resonate with today’s audience.

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While the plot may feel familiar to those who have watched similar thrillers, Thug Life distinguishes itself with its sharp direction, compelling performances, and high-quality production values. If you’re a fan of action films with emotional depth, this is a movie you won’t want to miss.

Rating: 4/5 – A must-watch for Kamal Haasan fans and action movie lovers alike.

Live Updates: Is Thug Life Making Waves?
10:00 AM – First Show Starts:
The first show has begun! Fans are already praising Kamal Haasan’s power-packed performance. Social media is flooded with reactions as people seem impressed with the intense action sequences.

12:30 PM – Early Box Office Numbers:
Thug Life is seeing a great response at the box office. Early reports show packed theaters in Chennai, Hyderabad, and Bengaluru. Looks like Kamal Haasan is in for a hit!

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3:00 PM – Social Media Buzz:
The film’s action and Kamal Haasan’s performance are trending on Twitter and Instagram. Fans are calling it his best role in years. Many are also impressed with the music by Anirudh.

6:00 PM – Fan Reactions:
The film continues to dominate social media as fans share videos from theaters. There’s a lot of love for the film’s emotional depth, making it clear that Thug Life is a crowd favorite.

Final Thoughts:
With such a fantastic opening, Thug Life looks set to make waves at the box office. Kamal Haasan’s stellar performance and the film’s impressive direction ensure that this thriller is more than just a typical action flick – it’s a cinematic experience.

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